1.
Chinese Journal of Nuclear Medicine and Molecular Imaging
;
(6): 627-631, 2019.
Artigo
em Chinês
| WPRIM
| ID: wpr-791572
RESUMO
Papillary thyroid cancer ( PTC) is the most common pathological type of thyroid cancer, and its morbidity raises rapidly in the global world. V-raf murine sarcoma viral oncogene homolog B1 ( BRAF) V600E mutation and telomerase reverse transcriptase ( TERT) promoter mutations are the most com-mon molecular markers of PTC. Nowadays, more and more studies find that the coexistence of BRAFV600E and TERT promoter mutations plays a synergistic role in the invasion and prognosis of PTC. This article re-views the recent advance in the synergism of BRAFV600E and TERT promoter mutations in PTC.